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PLANITI PLLA 1x365mg - Pre-Order

PLANITI PLLA 1x365mg - Pre-Order

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PLANITI is a CE-marked Poly-L-Lactic Acid (PLLA) dermal filler made from a biocompatible and biodegradable synthetic polymer, combining 150mg of PLLA, 90mg of Carboxymethylcellulose, and 125mg of non-pyrogenic Mannitol.

When injected, it acts as a bio-stimulator that activates the body’s own natural collagen production, with effects lasting up to 2 years. The PLLA is administered into the deepest layers of the skin, where it encourages collagen regeneration to restore volume, structure, and lift to skin.

Professional Use Only

Additional Information

Each vial of dry powder contains:
- 150mg of Poly-L-lactic acid
- 90mg of carboxymethylcellulose
- 125mg of non-pyrogenic mannitol

Indications:
- Deep dermal deficiencies
- Facial wrinkles & folds
- Marionette lines
- Temple
- Sagging jowls
- Scarring

Treatment Course:
- 3 consecutive sessions for longer lasting effect
- 1 month intervals between sessions

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Stimulate Collagen and Restore Facial Structure

PLANITI PLLA Dermal Filler is a professional injectable designed to rebuild and rejuvenate ageing skin from within. Using poly-L-lactic acid (PLLA), it acts as a bio-stimulator to promote natural collagen production, gradually restoring volume, firmness, and facial contours. By supporting the skin’s underlying structure, PLANITI improves elasticity, smooths fine lines, and enhances overall skin quality.

This advanced filler is suitable for use across the cheeks, jawline, chin, temples, and nasolabial folds, offering versatile treatment options for a wide range of aesthetic concerns. Administered by trained professionals, PLANITI delivers long-lasting, natural-looking results that evolve over time as collagen regeneration continues.

Regenerate, Restore & Redefine Skin Volume

PLANITI is an innovative poly-L-lactic acid (PLLA) dermal filler designed to rejuvenate and restore skin from within. Made from a biocompatible and biodegradable synthetic polymer, it works as a powerful collagen bio-stimulator, helping to rebuild the skin’s natural structure, volume, and elasticity over time. By targeting the deepest dermal layers, PLANITI promotes gradual, long-lasting regeneration - delivering results that look natural and evolve beautifully with the skin’s own biology.

Science-Led Skin Regeneration

Unlike traditional fillers that rely on immediate volume replacement, PLANITI stimulates fibroblast activity to encourage the body’s own collagen production. This process restores firmness, enhances elasticity, and smooths fine lines and wrinkles for a more youthful, lifted appearance. Clinical histopathological studies show active fibroblast migration and collagen proliferation from injection up to 48 weeks, confirming its effectiveness and safety. Inflammation levels were found to reduce from moderate to mild after 4 weeks, demonstrating excellent skin compatibility and tolerance.

PLANITI poly-L-lactic acid (PLLA) Dermal Filler FAQ's

What is PLANITI and how does it work?

PLANITI is a poly-L-lactic acid (PLLA) dermal filler that functions as a bio-stimulator rather than a traditional volumising filler. Once injected into the deep dermal or subcutaneous layers, the PLLA microparticles trigger fibroblast activity, stimulating natural collagen production. This process gradually restores skin firmness, elasticity, and structure, resulting in smoother, lifted, and more youthful-looking skin over time.

What areas can be treated with PLANITI?

PLANITI is designed for facial volume restoration and contour enhancement, particularly in areas affected by ageing or skin laxity. Common treatment zones include the cheeks, temples, jawline, chin, and nasolabial folds. Its collagen-stimulating action also improves overall skin texture and elasticity, making it suitable for patients seeking long-lasting skin rejuvenation rather than instant volumisation.

How many sessions are recommended, and when will results appear?

A standard treatment course typically involves 2 to 3 sessions, spaced 4 to 6 weeks apart. While some initial improvement may be visible immediately due to the carrier solution, the true results develop gradually as collagen synthesis increases - usually becoming noticeable from 4-6 weeks and continuing to improve for several months. Results can last up to 24 months, depending on individual factors such as age, lifestyle, and skin condition.

How does PLANITI differ from traditional hyaluronic acid fillers?

Unlike HA fillers that provide immediate volume by physically filling lines or hollows, PLANITI works by stimulating the body’s own collagen production for gradual, long-term rejuvenation. This leads to natural, durable improvements in skin structure without the “overfilled” appearance sometimes associated with HA fillers. Its effects are progressive and regenerative, offering firmness, lift, and texture enhancement that evolve over time.

How should practitioners prepare patients and the treatment area?

Conduct a full consultation and medical history to exclude contraindications (active infection, uncontrolled systemic disease, pregnancy/breastfeeding, known hypersensitivity to components). Mark treatment zones with the patient upright for accurate assessment. Use standard aseptic technique, cleanse thoroughly, and consider topical or local anaesthesia per clinic protocol to enhance comfort. Discuss realistic timelines - immediate changes vs progressive collagen stimulation - and obtain informed consent.

Can PLANITI be combined with other aesthetic treatments?

Yes, PLANITI integrates seamlessly into multi-modality treatment plans. It can complement other collagen-stimulating and skin-rejuvenating procedures such as skin boosters, polynucleotides, microneedling, and peels. Practitioners should space treatments appropriately to ensure optimal results and minimise irritation. This synergy allows clinicians to target both deep structural support and surface-level rejuvenation for comprehensive anti-ageing outcomes.

Read Our Protocol Documentation

For detailed guidance on injection techniques, dosage, and patient aftercare, download the full PLANITI Protocol Documentation and Professional eBook - your complete clinical resource for safe, effective, and confident treatment delivery.

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At HUK Aesthetics, we're committed to providing only the highest quality aesthetic injectables, ensuring every product we supply is 100% authentic, and, where required, CE certified. This guarantees our products meet or exceed the rigorous UK and European standards for safety, efficacy, and performance, giving our clients confidence in the treatments they provide.