AMI Tone Up 1x5ml Vial
AMI Tone Up 1x5ml Vial
AMI Tone Up combines the trusted quality of PN with added moisturising and brightening functions, offering an unparalleled experience that surpasses conventional skin boosters.
Skin Moisturising & Brightening
It enhances the overall skin tone, imparting a radiant glow from within, while effectively reducing the appearance of freckles and improving pigmentation for a noticeable tone-up effect.
Pain-Less Technology
This formulation features an increased PN (Polynucleotide) content and incorporates an advanced Pain-Less technology. Clinical trials have shown that despite the higher PN concentration (2.5mg/1ml), the procedure is significantly more comfortable, with reduced pain experienced by patients.
Vegan Exosome
This product also promotes fundamental skin improvement by strengthening the skin barrier, achieved through a collaboration with vegan exosomes. Its high-efficiency activation mechanism maximises the recovery of damaged skin and invigorates the skin's natural vitality.
Additionally, by utilising 'non-irritating' ingredients with a human skin reactivity and irritation index of 0.00 as key components, the product ensures stable and safe skin cell proliferation.
Professional Use Only
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Additional Information
Additional Information
INGREDIENTS
#1 Glutathione
Glutathione is a tripeptide made up of glycine, cysteine, and glutamic acid.
It is produced by the liver and is involved in several biological functions.
It is primarily used to reduce minor cosmetic defects, brighten the complexion, and correct uneven skin tone
#2 Tranexamic Acid
Tranexamic acid works to actively improve existing skin discolorations and also helps prevent the formation of new dark spots.
#3 Niacinamide
Niacinamide (nicotinamide) is a water-soluble form of vitamin B3 best known for its multiple skincare benefits.
As a skincare ingredient has potent anti-inflammatory, anti-acne, skin brightening, and anti-aging properties.
#4 Hyaluronic Acid
Hyaluronic Acid (HA) deeply hydrates the skin by retaining moisture and improving elasticity.
It reduces fine lines, promotes a youthful appearance, and is suitable for all skin types.
#5 PN (Sodium-DNA)
PN (PolyNucleotide) is a natural polymer derived from DNA that promotes skin regeneration and enhances collagen synthesis.
It reduces inflammation and stimulates cell activation, improving skin elasticity and hydration.
#6 Vegan Exosome
The exosome used in Ami Tone Up is a ‘non-irritating’ ingredient with a human skin reactivity and skin irritation index of 0.00, using ‘Pyeongpoom callus extracellular vesicles’ as its core raw material.
In addition to brightening agents, it also provides stable effects of vegan exosomes.
Plant-based exosomes not only retain the ability of stem cells to help skin cell recovery, but are also nano-sized and have the same phospholipid structure as cell membranes, so they are quickly absorbed by moving between cells.
High-efficiency activation maximises the recovery of damaged skin and boosts the skin's natural energy, allowing you to see a completely different skin condition after the treatment.
PROCEDURE
Mesotherapy: Use 30g or 32G needle, or 0.5ml or 1.0ml syringe.
Microneedlng: Yes
Treatment Course: 3 sessions with intervals of 15 days, plus 2 sessions with intervals of 1 month.

Shipping
At HUK Aesthetics, we are committed to ensuring your orders are processed quickly and efficiently.
All items are carefully packaged to maintain their quality during transit. Orders for in-stock items that are placed before 2.30PM, Monday to Friday (excluding Public and Bank Holidays), are usually processed and shipped the same day.
Shipping fees vary depending on your chosen service and destination, which will be clearly displayed at checkout. We work with DPD, Royal Mail, and The Pallet Network to ensure your orders arrive safely and on time.
Orders placed on a Saturday or Sunday are shipped on the following Monday (excluding Public and Bank Holidays).
We offer Free Standard Shipping on orders over £200 + VAT.
For shipping quotes overseas please contact us at hello@huk-aesthetics.com.
Delivery
We offer multiple delivery options to suit your needs, including standard and next-day delivery for UK addresses. Standard delivery typically takes 2–3 working days, while next-day delivery is available for in-stock item orders placed before 2.30PM, Monday to Friday (excluding Public and Bank Holidays).
Delivery times may vary during peak periods or due to unforeseen courier delays. Once your order has been dispatched, you will receive a tracking link to monitor its progress.
Please note: once your parcel has been dispatched, responsibility for the shipment passes to the customer. On the rare occasion that any issues arise with your courier or delivery, our team will happily liaise with your chosen courier on your behalf to assist in resolving the matter.
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Advanced Brightening and Skin Tone Support
AMI Tone Up is a next-generation skin booster designed to improve skin tone, radiance, and overall skin quality. Combining polynucleotides with moisturising and brightening ingredients, it helps enhance the appearance of dull, uneven, or pigmented skin for a clearer, more luminous complexion. With added Pain-Less technology and vegan exosome support, AMI Tone Up promotes skin barrier strength, supports damaged skin recovery, and helps revitalise the skin from within.
The Power of Polynucleotides (PDRN)
At the heart of AMI Tone Up is a powerful combination of polynucleotides, vegan exosomes, and brightening actives, designed to support skin regeneration while improving overall tone and radiance. This advanced formula helps hydrate and revitalise dull, uneven, or stressed skin, while ingredients such as glutathione, tranexamic acid, niacinamide, and hyaluronic acid work to promote a brighter, more luminous-looking complexion. Over time, AMI Tone Up helps restore skin quality from within, leaving the skin looking clearer, smoother, and visibly refreshed.
Advanced Skin Brightening with AMI Tone Up: Illuminate, Even, Revitalise
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Brightening and Tone Correction
The primary focus of AMI Tone Up is to support a brighter, more even-looking complexion. Designed for dull, uneven, or pigmentation-prone skin, this treatment works to improve skin clarity, reduce the appearance of dark spots, and restore a fresher, more radiant glow. With brightening ingredients such as glutathione, tranexamic acid, and niacinamide, AMI Tone Up helps the skin look clearer, smoother, and more luminous over time.
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Polynucleotide and Exosome Skin Support
AMI Tone Up combines polynucleotides with plant-based exosomes to help support skin regeneration, repair, and overall skin quality. This advanced formula helps revitalise tired or stressed skin from within, improving the appearance of texture, hydration, and resilience. The result is skin that looks healthier, more balanced, and visibly refreshed.
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Hydration, Radiance, and Skin Barrier Care
AMI Tone Up is also designed to deeply hydrate and condition the skin, helping to improve softness, smoothness, and luminosity. With hyaluronic acid and skin-supporting ingredients, it helps maintain moisture while supporting the skin barrier. This makes it an ideal choice for patients looking to achieve a brighter, dewier, and more revitalised complexion without adding volume.
Strengthened Skin Barrier and Environmental Defence
Beyond its brightening and hydrating benefits, AMI Tone Up helps support the skin’s natural barrier for a healthier, more resilient complexion. By combining polynucleotides, vegan exosomes, and skin-supporting actives, it encourages cellular repair while helping the skin better withstand daily environmental stressors such as pollution, dryness, and UV exposure. This protective support helps maintain a clearer, brighter, and more radiant appearance over time.
AMI Tone Up FAQs
How soon will I see results after AMI Tone Up treatment?
Some patients may notice improved hydration and radiance shortly after treatment, with the skin appearing fresher and more luminous. Brightening and tone-improving results usually develop gradually over the following days and weeks as the skin responds to the polynucleotides, vegan exosomes, and brightening actives.
Is AMI Tone Up suitable for sensitive skin?
AMI Tone Up is designed to support skin quality, hydration, and barrier function, making it suitable for a wide range of skin types, including dull, stressed, or sensitive-looking skin. Suitability should always be assessed by a qualified practitioner, especially for patients with reactive skin or specific skin concerns.
Can AMI Tone Up be combined with other aesthetic treatments?
Yes, AMI Tone Up may be incorporated into wider skin rejuvenation plans and combined with other aesthetic treatments where appropriate. A trained practitioner can advise on the best treatment timings and combinations based on the patient’s skin condition, goals, and treatment history.
How long does each AMI Tone Up treatment session take?
Treatment times can vary depending on the area being treated and the practitioner’s technique, but AMI Tone Up sessions are typically relatively quick. Most appointments can usually be completed within a short clinic visit, including consultation, preparation, and treatment.
Are there any side effects from AMI Tone Up?
As with many injectable skin booster treatments, patients may experience mild temporary effects such as redness, swelling, tenderness, small bumps, or bruising at the injection sites. These effects are usually short-lived and should be discussed with a qualified practitioner before treatment.
How many treatments are recommended for best results?
The recommended number of AMI Tone Up treatments can vary depending on the patient’s skin condition and desired outcome. A course of sessions is often advised for optimal brightening, hydration, and skin-quality improvement, followed by maintenance treatments as recommended by the practitioner.
AMI Tone Up Protocol Documentation
A complete guide to AMI Tone Up, highlighting its advanced approach to brightening, skin quality, and regenerative support, with key treatment benefits and resources to help you confidently introduce this tone-enhancing treatment into your clinic.
Testimonials
Glutathione, hyaluronic acid, polypeptide, amino acid and other active ingredients are added simultaneously to provide healthy, youthful and brightly shining skin through overall cell replacement from the inside out in the order the skin need. See the results yourself:
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