Collection: Nucleofill
Nucleofill – Regeneration, Hydration & Lifting from Within
Nucleofill is a cutting-edge bio-stimulating skin booster designed to improve skin quality, restore hydration, and stimulate cellular renewal. Powered by polynucleotides, Nucleofill works beneath the surface to regenerate the skin, enhance elasticity, and deliver a lifting effect, making it a trusted solution for aesthetic professionals seeking natural, long-lasting results.
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Nucleofill 25 (Nucleofill Strong Replacement)
Regular price £44.99Regular priceUnit price / perSold out -
Nucleofill 20 (Nucleofill Medium Replacement)
Regular price £39.99Regular priceUnit price / per£44.99Sale price £39.99Sold out -
Nucleofill Hair (Nucleofill Medium Plus Replacement)
Regular price £41.99Regular priceUnit price / per£44.99Sale price £41.99Sold out -
Nucleofill Eye (Nucleofill Soft Plus Replacement)
Regular price £44.99Regular priceUnit price / perSold out -
Skin Boosters

Introducing Nucleofill: Advanced Skin Bio-Stimulation
Nucleofill is a revolutionary range of natural, polynucleotide-based bio-stimulating gels designed to protect, hydrate, and rejuvenate the skin from within. Unlike traditional fillers, Nucleofill works at the cellular level to stimulate skin regeneration, boost collagen and elastin production, and neutralise free radicals, resulting in firmer, smoother, and more radiant skin. With its unique lifting, antioxidant, and hydrating properties, Nucleofill offers a natural, long-lasting solution for clients seeking to restore youthful vitality without adding volume.
Shop the Nucleofill Range
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Nucleofill 20
SHOP HERENucleofill 20 (formerly Nucleofill Medium) is a bio-stimulating injectable treatment enriched with polynucleotides, designed to reduce the visible signs of aging. It promotes skin regeneration and repairs cellular damage, leaving the skin looking more youthful and radiant.
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Nucleofill 25
SHOP HERENucleofill 25 (formerly Nucleofill Strong) is an advanced injectable polynucleotide (PN) treatment designed to rejuvenate the skin and reduce the visible signs of aging. This powerful bio-stimulator works by promoting cellular regeneration, replenishing hydration to dull skin, and gradually releasing collagen for long-lasting, natural results.
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Nucleofill Hair
SHOP HERENucleofill Hair (formerly Nucleofill Medium Plus) is an advanced polynucleotide injectable designed to promote hair growth and combat hair loss. This treatment works by stimulating hair follicles and enhancing blood circulation, helping restore hair to its natural strength, health, and thickness.
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Nucleofill Eye
SHOP HERENucleofill Soft Plus is specifically designed to treat the delicate eye area, offering a rejuvenating solution for this sensitive part of the face. This dermal filler effectively addresses small wrinkles and dark circles under the eyes, leaving the skin looking smoother and more radiant.

The Key Benefits of Nucleofill
Nucleofill offers a powerful combination of skin regeneration, deep hydration, and antioxidant protection to rejuvenate and revitalise the skin from within. By stimulating collagen and elastin production, it improves skin elasticity and firmness, reducing the appearance of fine lines and wrinkles. Its unique ability to neutralise free radicals helps slow down the ageing process, while its high viscosity ensures long-lasting moisturisation for a plumper, more radiant complexion. Suitable for all skin types, Nucleofill provides natural, long-lasting results with minimal downtime, making it an ideal choice for those seeking a non-invasive yet effective skin treatment.
Nucleofill FAQs
What is Nucleofill?
Nucleofill is a range of advanced polynucleotide-based bio-stimulating gels designed to rejuvenate and hydrate the skin by promoting cellular regeneration and protecting against free radical damage.
How is Nucleofill different from traditional dermal fillers?
Unlike dermal fillers, which add volume to the skin, Nucleofill works by stimulating the skin’s natural repair processes, improving elasticity, hydration, and skin quality without altering facial contours.
What are polynucleotides and why are they important?
Polynucleotides are natural organic compounds that are key components of DNA. They help repair and regenerate cells, stimulate collagen and elastin production, and improve skin hydration.
Which skin concerns can Nucleofill address?
Nucleofill is effective for treating fine lines, wrinkles, sagging skin, dehydration, dull complexion, scars, stretch marks, and under-eye puffiness.
How long do the results last?
Results typically last between 6 to 12 months, depending on individual skin condition and treatment protocol.
Is there any downtime after treatment?
Nucleofill treatments involve minimal downtime, making it suitable for clients with busy lifestyles who want effective, natural-looking results without lengthy recovery.
How many treatments are usually required?
A typical course involves 2 to 4 treatments spaced 2 to 4 weeks apart, with maintenance sessions recommended every 6 to 9 months.
Is Nucleofill suitable for all skin types?
Yes, Nucleofill is formulated to be safe and effective for all skin types and tones.


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HUK Aesthetics is a 5-star trusted business, known for our reliable service, fast shipping, and unbeatable prices.
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All our products are certified and meet the required standards
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Cost effective without compromising on quality
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A dedicated customer service team to help you at any time
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Next day delivery on orders placed pre-1pm Monday - Friday