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Nucleofill 25 (Nucleofill Strong Replacement)

Nucleofill 25 (Nucleofill Strong Replacement)

£44.99
£44.99
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Nucleofill 25 (formerly Nucleofill Strong) is an advanced injectable polynucleotide (PN) treatment designed to rejuvenate the skin and reduce the visible signs of aging. This powerful bio-stimulator works by promoting cellular regeneration, replenishing hydration to dull skin, and gradually releasing collagen for long-lasting, natural results.

Professional Use Only

Additional Information

Ideal for anyone looking to restore youthful vitality, Nucleofill 25 enhances skin elasticity, firmness, and radiance. Formulated with fish DNA, which closely resembles human DNA, Nucleofill 25 activates fibroblasts to boost collagen and elastin production. These key proteins are vital for tissue regeneration and structural integrity, allowing the skin to heal and regenerate naturally.

Nucleofill 25 is suitable for all skin types and can be used to address fine lines, wrinkles, and overall skin tone, leaving the skin looking smoother, tighter, and more luminous.

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Nucleofill 25: Deep Regeneration for Ageing Skin

Nucleofill 25 is a powerful polynucleotide-based injectable designed to treat moderate to advanced signs of ageing. With a 2.5% concentration of polynucleotides, it works beneath the surface to stimulate collagen and elastin production, enhance skin elasticity, and improve overall tone and texture. By encouraging natural tissue regeneration, Nucleofill 25 helps to soften fine lines, restore hydration, and support long-term skin health - delivering visible results without altering facial expression.

Advanced Bio-Stimulation with Lasting Results

Formulated from fish DNA fragments that closely resemble human DNA, Nucleofill 25 activates fibroblasts, promotes cell turnover, and improves the skin’s structural integrity. Suitable for all skin types, it effectively treats dullness, pigmentation, scars, and mild laxity across the face, neck, and décolletage. As a non-invasive alternative to fillers or surgery, Nucleofill 25 provides progressive, natural-looking rejuvenation with minimal downtime - making it a trusted choice for practitioners and clients seeking high-performance skin renewal.

The Power of Nucleofill 25

  • High-Strength Cellular Renewal

    Nucleofill 25 (formerly Nucleofill Strong) is a next-generation bio-stimulating injectable that targets deeper signs of ageing with a concentrated 2.5% polynucleotide formula. This higher-strength solution works by activating fibroblast cells, encouraging the production of collagen and elastin, and promoting deep tissue regeneration. The result is firmer, healthier-looking skin with visibly improved tone and structure—ideal for clients seeking natural yet noticeable rejuvenation.

  • Collagen Boosting for Long-Lasting Rejuvenation

    By stimulating the skin’s natural regenerative functions, Nucleofill 25 delivers gradual and sustained results. Unlike traditional dermal fillers, it doesn’t add volume but instead works to strengthen the skin from within. As new collagen is produced, the skin becomes smoother, tighter, and more resilient - making this treatment especially effective for addressing fine lines, scarring, and early skin laxity across the face, neck, and décolletage.

  • A Safe and Versatile Anti-Ageing Solution

    Suitable for all skin types, Nucleofill 25 offers a non-invasive approach to skin revitalisation with minimal downtime and a low risk of side effects. Its DNA-derived polynucleotides, sourced from fish, are biocompatible and well-tolerated, making this an excellent option for clients seeking a gentler alternative to injectables or surgery. Whether used preventatively or as part of a corrective protocol, Nucleofill 25 is a trusted solution for restoring hydration, brightness, and skin integrity over time.

The Benefits of Nucleofill 25

Collagen and elastin stimulation:
Promotes firmer, more resilient skin

Deep hydration:
Revives dull, dehydrated skin for a radiant appearance

Improved elasticity and texture:
Reduces sagging and improves overall skin quality

Fine lines and wrinkles:
Minimises visible signs of ageing

Scars and pigmentation:
Helps reduce the appearance of scars, stretch marks, and uneven tone

Skin brightness:
Enhances tone for a smoother, more even complexion

Tissue regeneration:
Supports gradual, natural skin repair from within

Non-volumising effect:
Preserves natural facial contours and expressions

Versatile application:
Suitable for all skin types and areas including face, neck, and décolletage

Minimal downtime:
Low risk of side effects with quick recovery

Shop the Nucleofill Range

  • Nucleofill 20

    Nucleofill 20 (formerly Nucleofill Medium) is a bio-stimulating injectable treatment enriched with polynucleotides, designed to reduce the visible signs of aging. It promotes skin regeneration and repairs cellular damage, leaving the skin looking more youthful and radiant.

    SHOP HERE

  • Nucleofill 25

    Nucleofill 25 (formerly Nucleofill Strong) is an advanced injectable polynucleotide (PN) treatment designed to rejuvenate the skin and reduce the visible signs of aging. This powerful bio-stimulator works by promoting cellular regeneration, replenishing hydration to dull skin, and gradually releasing collagen for long-lasting, natural results.

    SHOP HERE

  • Nucleofill Hair

    Nucleofill Hair (formerly Nucleofill Medium Plus) is an advanced polynucleotide injectable designed to promote hair growth and combat hair loss. This treatment works by stimulating hair follicles and enhancing blood circulation, helping restore hair to its natural strength, health, and thickness.

    SHOP HERE

  • Nucleofill Eye

    Nucleofill Soft Plus is specifically designed to treat the delicate eye area, offering a rejuvenating solution for this sensitive part of the face. This dermal filler effectively addresses small wrinkles and dark circles under the eyes, leaving the skin looking smoother and more radiant.

    SHOP HERE

Nucleofill 25 FAQs

What is Nucleofill 25?

Nucleofill 25 is a high-strength polynucleotide injectable (formerly known as Nucleofill Strong) designed to rejuvenate the skin, stimulate collagen production, and improve overall skin health and hydration. It is a bio-stimulator, meaning it encourages the skin to regenerate naturally over time.

Who is Nucleofill 25 suitable for?

It is ideal for individuals with moderate to advanced signs of ageing, such as fine lines, wrinkles, skin laxity, and dullness. Suitable for all skin types, it can be used on areas such as the face, neck, and décolletage.

How does it differ from Nucleofill 20?

The main difference lies in the concentration of polynucleotides - Nucleofill 25 contains 2.5%, compared to 2% in Nucleofill 20. This makes it more suitable for clients requiring a stronger, more intensive treatment.

How many treatments are needed?

A typical protocol includes 2 to 4 sessions, spaced around 2 to 4 weeks apart, depending on skin condition and desired results. Maintenance sessions may be recommended every 4 to 6 months.

Is there any downtime?

Downtime is minimal. Some clients may experience mild redness, swelling, or tenderness at the injection sites, but these effects usually subside within 24 to 48 hours.

Can it be combined with other treatments?

Yes, Nucleofill 25 can be safely combined with other aesthetic procedures such as microneedling, PRP, mesotherapy, or light chemical peels to enhance results.

How soon will I see results?

Results appear gradually, with improved skin texture, tone, and hydration often visible after the first or second session. As collagen production continues, full results develop over several weeks.

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At HUK Aesthetics, we're committed to providing only the highest quality aesthetic injectables, ensuring every product we supply is 100% authentic, and, where required, CE certified. This guarantees our products meet or exceed the rigorous UK and European standards for safety, efficacy, and performance, giving our clients confidence in the treatments they provide.