Plinest Polynucleotides Explained: Types, Benefits, and How to Use Them for Skin and Hair Regeneration
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At HUK Aesthetics, we’re proud to support clinics with products that don’t just treat the surface — they restore skin from the inside out. One of the standout regenerative injectables in our portfolio is Plinest, a trusted polynucleotide-based treatment that helps repair, regenerate, and rejuvenate the skin at a cellular level.
If you’re looking to elevate your skin booster offerings with a scientifically-backed, results-driven solution, Plinest deserves a spot on your shelf.
What is Plinest?
Plinest is a skin regeneration injectable made with high-purity polynucleotides (PNs), derived from purified salmon DNA. These naturally occurring molecules are renowned for their ability to stimulate fibroblast activity, which enhances the production of collagen, elastin, and hyaluronic acid — key components of youthful, healthy skin.
Unlike fillers that volumise or skin boosters that hydrate, Plinest works on a deeper regenerative level, making it ideal for:
- Photo-aged or environmentally damaged skin
- Acne scarring and texture irregularities
- Loss of elasticity and thinning skin
- Dark circles and periorbital ageing
- Hair loss or scalp health support
- Pre- and post-surgical skin recovery
The Plinest Range at HUK Aesthetics
We stock several Plinest formulations, each designed for different treatment areas and patient needs. Here’s a breakdown of the range and how to use them effectively:
1. Plinest 2ml 20mg/ml (2.5%) PN-HPT
Best for: General facial rejuvenation and overall skin quality
- Improves tone, texture, and elasticity
- Hydrates and softens early signs of ageing
- Suitable for face, neck, and décolletage
2–4 treatments, spaced 2–3 weeks apart
2. Plinest Fast
Best for: Delicate areas like the under-eyes and upper lip
- Fast absorption and gentle diffusion
- Brightens and firms sensitive skin
- Ideal for low-downtime or subtle treatments
2–3 treatments, spaced 2–3 weeks apart
3. Plinest Eye
Best for: Under-eye rejuvenation and dark circles
Plinest Eye is specially formulated for the fragile periorbital area, offering gentle but effective regeneration. It reduces dark circles, fine lines, and puffiness by boosting skin density and microcirculation.
- Improves brightness and elasticity
- Strengthens thin under-eye skin
- Non-volumising — perfect for tear trough treatment
Used alone or as an alternative to tear trough filler
1–3 treatments, spaced 2–3 weeks apart
4. Plinest Hair
Best for: Hair loss, scalp health, and follicle stimulation
Plinest Hair is a regenerative solution for scalp revitalisation and hair density support. Using polynucleotides to improve microcirculation and nourish follicles, it’s ideal for patients experiencing thinning hair or as part of a wider hair loss protocol.
-Stimulates scalp regeneration
- Strengthens and supports hair follicles
- Enhances scalp hydration and circulation.
Suitable for use on its own or combined with microneedling.
3–5 sessions depending on severity, spaced 1–2 weeks apart
Why Choose Plinest?
Plinest is more than just a skin treatment — it’s a true regenerative therapy, ideal for clinics focusing on long-term skin health and repair. Practitioners love Plinest for its:
- Scientifically backed polynucleotide technology
- Safe, biocompatible formulas suitable for all skin types
- Ability to treat difficult areas like under-eyes, scars, and scalps
- Minimal downtime with natural-looking results
- Flexibility across facial and body indications